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{"id":48602,"date":"2020-11-04T15:45:21","date_gmt":"2020-11-04T14:45:21","guid":{"rendered":"https:\/\/www.ubfc.fr\/?page_id=48602"},"modified":"2021-01-20T11:42:38","modified_gmt":"2021-01-20T10:42:38","slug":"labex-lipstic","status":"publish","type":"page","link":"https:\/\/ubfc-preprod.u-bourgogne.fr\/recherche\/projets-de-recherche\/pia\/labex-lipstic\/","title":{"rendered":"LabEx LipSTIC"},"content":{"rendered":"\t\t
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Les lipoprot\u00e9ines ont fait l\u2019objet de nombreux travaux dans le domaine cardio-vasculaire. Dans les ann\u00e9es 1950, le transport du cholest\u00e9rol par celles-ci constituait un sujet de recherche attractif. Ainsi, les LDL ont \u00e9t\u00e9 identifi\u00e9es comme un facteur de risque majeur alors que de nombreux travaux \u00e9pid\u00e9miologiques ont mis en \u00e9vidence le r\u00f4le \u00ab\u00a0protecteur\u00a0\u00bb des HDL.<\/strong><\/p>
Ce n\u2019est que r\u00e9cemment que l\u2019implication et la fonction des lipoprot\u00e9ines dans le cancer et les maladies inflammatoires a \u00e9t\u00e9 d\u00e9montr\u00e9 : les LDL et les HDL sont \u00e9galement des facteurs pronostiques lors des cancers et de certaines maladies inflammatoires ou infectieuses. De ces d\u00e9couvertes r\u00e9centes d\u00e9coule un int\u00e9r\u00eat croissant pour les lipoprot\u00e9ines.<\/p>
L\u2019utilisation de ces complexes mol\u00e9culaires pour pr\u00e9venir, diagnostiquer ou traiter le cancer et les maladies inflammatoires mobilise et f\u00e9d\u00e8re les \u00e9quipes du Labex LipSTIC.<\/p>
Le LabEx (Lab<\/strong>oratoires d\u2019Ex<\/strong>cellence) est un instrument du Programme d\u2019Investissement d\u2019Avenir. Il a pour objectif\u00a0:<\/p>
de fournir des moyens significatifs aux unit\u00e9s de recherche afin de faire jeu \u00e9gal avec leurs homologues \u00e9trangers,<\/li>
d\u2019attirer des chercheurs et enseignants chercheurs de renomm\u00e9e internationale,<\/li>
de construire une politique int\u00e9gr\u00e9e de recherche, de formation et de valorisation de haut niveau, ainsi qu\u2019une politique de large diffusion des connaissances.<\/li><\/ul><\/li><\/ul>
LipSTIC\u00a0: Lipoprot\u00e9ines et Sant\u00e9, pr\u00e9vention et Traitement des maladies Inflammatoires et du Cancer<\/strong><\/li><\/ul>