{"id":50826,"date":"2021-01-20T11:38:06","date_gmt":"2021-01-20T10:38:06","guid":{"rendered":"https:\/\/www.ubfc.fr\/labex-lipstic\/"},"modified":"2021-01-20T11:41:21","modified_gmt":"2021-01-20T10:41:21","slug":"labex-lipstic","status":"publish","type":"page","link":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/investment-program-for-the-future-programme-dinvestissement-davenir-pia\/labex-lipstic\/","title":{"rendered":"LabEx LipSTIC"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"50826\" class=\"elementor elementor-50826\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2fa78f5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2fa78f5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6c01b95\" data-id=\"6c01b95\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e585cf1 elementor-widget elementor-widget-text-editor\" data-id=\"e585cf1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Lipoproteins have been extensively studied in the cardio-vascular field. In the 1950\u2019s, the transport of cholesterol by lipoproteins was an attractive research topic. LDLs were identified as a major risk factor, while numerous epidemiological works highlighted the \u201cprotective\u201d role of HDLs.<\/strong><\/p>\n<p>The involvement and function of lipoproteins in cancer and inflammatory diseases was only evidenced recently. LDLs and HDLs are also prognostic factors of cancers or certain inflammatory or infectious diseases. These recent findings have brought about an increasing interest in lipoproteins.<\/p>\n<p>The use of these molecular complexes to prevent, diagnose or treat cancer and inflammatory diseases mobilises and federates the LIPSTIC Labex teams.<\/p>\n<p>&nbsp;<\/p>\n<ul style=\"list-style-type: square;\">\n<li><strong>What is a LabEx?<\/strong><\/li>\n<\/ul>\n<p>A LabEx (<strong>Lab<\/strong>oratory of <strong>Ex<\/strong>cellence) is part of the Investment Program for the Future. Its objectives are the following ones:<\/p>\n<ul style=\"list-style-type: circle;\">\n<li>to provide significant means to research units for them to be on a par with their foreign counterparts<\/li>\n<li>to attract researchers and lecturers-researchers of international renown<\/li>\n<li>to build an integrated, high-level policy of research, training and valorisation aimed at large dissemination of knowledge.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul style=\"list-style-type: square;\">\n<li><strong>LipSTIC: Lipoproteins and health, prevention and treatment of inflammatory diseases and cancer<\/strong><\/li>\n<\/ul>\n<p>LipSTick is a multidisciplinary research program unique in France. It gathers 23 research teams.<br \/>\nIts main objective is to contribute to the fight against the scourge of cancer, but also to make advances in the fields of transplant and inflammation.<\/p>\n<p>It relies on the original and ambitious idea to use <a href=\"http:\/\/www.labex-lipstic.fr\/node\/256\">lipoproteins<\/a> to:<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li>prevent the occurrence and progression of non-vascular pathologies such as cancer and inflammatory diseases<\/li>\n<li>transport insoluble bioactive molecules (lipids or drugs) in water matrices to the target diseased organ<\/li>\n<li>neutralise and transport pro-inflammatory bacterial compounds to the liver for them to be eliminated.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>This research is organised around 5 main lines of research directly addressing lipoproteins and 3 cross-cutting ones aimed at accelerating the social and economic impacts of this newly acquired knowledge.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b337349 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b337349\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ed9f404\" data-id=\"ed9f404\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-89cf065 elementor-widget elementor-widget-image\" data-id=\"89cf065\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"943\" height=\"564\" src=\"https:\/\/ubfc-preprod.u-bourgogne.fr\/wp-content\/uploads\/2020\/03\/WP_lipSTIC.png\" class=\"attachment-large size-large wp-image-42632\" alt=\"WP_LipSTIC\" srcset=\"https:\/\/ubfc-preprod.u-bourgogne.fr\/wp-content\/uploads\/2020\/03\/WP_lipSTIC.png 943w, https:\/\/ubfc-preprod.u-bourgogne.fr\/wp-content\/uploads\/2020\/03\/WP_lipSTIC-300x179.png 300w, https:\/\/ubfc-preprod.u-bourgogne.fr\/wp-content\/uploads\/2020\/03\/WP_lipSTIC-768x459.png 768w\" sizes=\"(max-width: 943px) 100vw, 943px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-72f60a6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"72f60a6\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c5aa729\" data-id=\"c5aa729\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8e94512 elementor-widget elementor-widget-text-editor\" data-id=\"8e94512\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>More information on this project supported by UBFC and its lines of research on the LabEx LipSTIC <a href=\"http:\/\/www.labex-lipstic.fr\/\">website<\/a>.<\/p>\n<p><strong>Contact<\/strong>:<br \/>\n<a href=\"philippe.saas@efs.sante.fr\">Philippe SAAS<\/a><br \/>\nLabEx LipSTIC coordinator<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-medium wp-image-42724\" src=\"https:\/\/www.ubfc.fr\/wp-content\/uploads\/2020\/03\/ANR_Lipstic_GRAND-300x137.jpg\" alt=\"\" width=\"300\" height=\"137\" srcset=\"https:\/\/ubfc-preprod.u-bourgogne.fr\/wp-content\/uploads\/2020\/03\/ANR_Lipstic_GRAND-300x137.jpg 300w, https:\/\/ubfc-preprod.u-bourgogne.fr\/wp-content\/uploads\/2020\/03\/ANR_Lipstic_GRAND.jpg 339w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><br \/>\n<span id=\"OBJ_PREFIX_DWT10692_ZmEmailObjectHandler\" class=\"Object\" role=\"link\"><span id=\"OBJ_PREFIX_DWT10699_ZmEmailObjectHandler\" class=\"Object\" role=\"link\">\u00a0<\/span><\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Lipoproteins have been extensively studied in the cardio-vascular field. In the 1950\u2019s, the transport of cholesterol by lipoproteins was an attractive research topic. LDLs were identified as a major risk factor, while numerous epidemiological works highlighted the \u201cprotective\u201d role of HDLs. The involvement and function of lipoproteins in cancer and inflammatory diseases was only evidenced &hellip; <a href=\"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/investment-program-for-the-future-programme-dinvestissement-davenir-pia\/labex-lipstic\/\">Continued<\/a><\/p>\n","protected":false},"author":18,"featured_media":0,"parent":50844,"menu_order":38,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-50826","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages\/50826","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/comments?post=50826"}],"version-history":[{"count":1,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages\/50826\/revisions"}],"predecessor-version":[{"id":50827,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages\/50826\/revisions\/50827"}],"up":[{"embeddable":true,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages\/50844"}],"wp:attachment":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/media?parent=50826"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}