{"id":33931,"date":"2019-03-05T09:24:38","date_gmt":"2019-03-05T08:24:38","guid":{"rendered":"http:\/\/www.ubfc.fr\/?page_id=33931"},"modified":"2020-07-16T15:16:11","modified_gmt":"2020-07-16T13:16:11","slug":"open-resarch-projects","status":"publish","type":"page","link":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/open-resarch-projects\/","title":{"rendered":"Open research projects"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"33931\" class=\"elementor elementor-33931\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1d987dd elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1d987dd\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c5df8a5\" data-id=\"c5df8a5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ac3d30c elementor-widget elementor-widget-toggle\" data-id=\"ac3d30c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1801\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1801\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">HERMES - Spatiotemporal semantics and logical knowledge description of mecHanical objEcts in the era of 4D pRinting and programmable Matter for nExt-generation of CAD systemS <\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1801\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1801\"><p>An innovative trend promoted by the unique capabilities of additive manufacturing techniques is about the \u201c4D Printing\u201d concept. It is actually the process by which assemblies and parts embodying smart materials are printed, they are therefore able to react to changes in their environment. As a new way of<br \/>thinking and manufacturing method, few is known about how to systematically bring such smart products ideas into reality.<\/p><p>The HERMES research project aims at introducing a general framework for designing 4D printed solutions. It delineates the research effort to be made so that designers are sufficiently empowered to design such smart products. The ultimate goal of HERMES is to extend current CAD systems capabilities to fully embrace 4D printing opportunities and the increase of reasoning capacities embedded in systems and matter.<\/p><p><strong>Coordinator :<\/strong><br \/>Fr\u00e9d\u00e9ric DEMOLY<br \/>UTMB \/ ICB<br \/><a href=\"mailto:frederic.demoly@utbm.fr\">frederic.demoly@utbm.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>Le2i<\/li><li>UTMB<\/li><li>uB<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1802\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-1802\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">MYAV - Motivic invariants of algebraic varieties<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1802\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-1802\"><p>It is a major insight of the preceding two centuries that one can use a geometrical language to study the solutions of a given set of polynomial equations with coefficients in an arbitrary field, such as the complex numbers or even in an arbitrary ring, such as the integers. The corresponding objects,<br \/>called algebraic varieties, are extremely rich and mysterious due to their<br \/>dual nature, geometric and arithmetic.<br \/>The driving force of the project is the use of the recent and powerful theory of motivic A1-homotopy introduced by Voevodsky to produce new, and study classical, invariants of algebraic varieties of both geometric and arithmetic nature.<br \/>The expected applications have a very wide range: advances in the understanding of Voevodsky\u2019s theory, producing new knowledge in affine algebraic geometry, extending previously known computations of invariants for families of algebraic varieties, and improvement of our arithmetical knowledge of certain kinds of algebraic varieties.<\/p><p><strong>Coordinator :<\/strong><br \/>Fr\u00e9d\u00e9ric DEGLISE<br \/>CNRS \/ IMB<br \/><a href=\"mailto:frederic.deglise@u-bourgogne.fr\">frederic.deglise@u-bourgogne.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>uB<\/li><li>UFC<\/li><li>CNRS<\/li><li>LMB<\/li><\/ul><p>\u00a0<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1803\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"button\" aria-controls=\"elementor-tab-content-1803\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">LIPOMAC - LXR-mediated phospholipid remodeling and macrophage functions: relevance in the context of cardio-metabolic and autoimmune diseases<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1803\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"region\" aria-labelledby=\"elementor-tab-title-1803\"><p>Liver X receptors (LXRs) are oxysterol-activated nuclear receptors involved in the regulation of cholesterol homeostasis and in the control of inflammation.<br \/>The general goal of this project is to assess how modulation of fatty acid metabolism by LXRs affects macrophage functions in the context of cardio-metabolic diseases and auto-immune diseases with a specific emphasis on the secretion of pro- and anti-inflammatory lipid mediators and efferocytosis (clearance of apoptotic cells by macrophages).<\/p><p><strong>Coordinator :<\/strong><br \/>David MASSON<br \/>CHU Dijon, UMR 1231 LNC, EFS<br \/><a href=\"mailto:david.masson@chu-dijon.fr\">david.masson@chu-dijon.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>CHU Dijon<\/li><li>uB<\/li><li>University of Franche-Comt\u00e9<\/li><li>INSERM<\/li><li>EFS<\/li><\/ul><p>\u00a0<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1804\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"button\" aria-controls=\"elementor-tab-content-1804\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">IATEKA - Interdisciplinary approach to the territorial evolution of the Kvarner archipelago<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1804\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"region\" aria-labelledby=\"elementor-tab-title-1804\"><p>The islands have the advantage of being geographically well defined spaces, possessing their own particular ecosystems and well definable network of sites and landscape marks. As such, Kvarner archipelago (Croatia, northern Adriatic), has been chosen as the case-study region for the IATEKA project.<br \/>These islands are already in the focus of ongoing historical and archaeological research concentrated on the territories of two sites : Mirine-Fulfinum (island of Krk), occupied between 1st and 9th c. AD, and the city of Osor (island of Cres), occupied without interruption since the protohistoric oppidum to the present<br \/>day. This classical approach will be highly enriched and complemented by IATEKA project.<\/p><p>By combining the obtained data from archaeological, anthropological, palynological and more globally paleoenvironmental research, the main goal of this project is to find relevant markers that are likely to provide the elements for the renewed and unprecedented understanding of population dynamics and itsconsequence on the evolution of these islands natural and anthropic environments.<\/p><p><strong>Coordinator :<\/strong><br \/>Morana CAUSEVIC BULLY<br \/>UFC \/ Chrono-environnement<br \/><a title=\"morana.causevic-bully..\u00e5t..univ-fcomte.fr\" href=\"https:\/\/chrono-environnement.univ-fcomte.fr\/spip.php?page=perso&amp;nom=CAUSEVIC-BULLY&amp;prenom=Morana#morana.causevic-bully#mc#univ-fcomte.fr#\">morana.causevic-bully<span class=\"mcrypt\">@<\/span>univ-fcomte.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>ArTeHiS<\/li><li>Biogeosciences<\/li><li>DRASSM Marseille<\/li><li>MDAA Besan\u00e7on<\/li><li>University of Franche-Comt\u00e9<\/li><li>uB<\/li><li>CNRS<\/li><li>Institute for Anthropology (Zagreb)<\/li><li>University of Bradfort<\/li><li>University of Padova<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1805\" class=\"elementor-tab-title\" data-tab=\"5\" role=\"button\" aria-controls=\"elementor-tab-content-1805\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">INVACLIM - Interindividual variation in behavioural and physiological responses of invasive invertebrate species to climate change in Burgundy<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1805\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"5\" role=\"region\" aria-labelledby=\"elementor-tab-title-1805\"><p>The possibility that climate change exacerbates the impact of invasive species at the expense of native ones is of major concern for Conservation biologists. The<br \/>team proposes to develop a multidisciplinary approach to examine the impact of increased temperature and temperature variability on two invertebrate invading<br \/>species in Burgundy (the spotted wing fly, Drosophila suzukii and the freshwater crustacean amphipod, Gammarus roeseli), and their \u00abrival\u00bb native species D.<br \/>melanogaster and G. fossarum.<\/p><p><strong>Coordinator :<\/strong><br \/>Franck CEZILLY<br \/>uB \/ Biog\u00e9osciences<br \/><a href=\"mailto:franck.cezilly@u-bourgogne.fr\">franck.cezilly@u-bourgogne.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>Chrono-environnement<\/li><li>CSGA<\/li><li>uB<\/li><li>CNRS<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1806\" class=\"elementor-tab-title\" data-tab=\"6\" role=\"button\" aria-controls=\"elementor-tab-content-1806\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">NOISE LESS - Structure, function and roles of nitric oxide synthases in algal responses to environmental stresses<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1806\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"6\" role=\"region\" aria-labelledby=\"elementor-tab-title-1806\"><p>The project aims at deciphering the structural, enzymatic and biochemical properties of new Nitric oxides and to investigate their regulation and roles in selected algae. A special focus will be given to their involvement in algae growth, innate immunity and response to abiotic stresses.<\/p><p><strong>Coordinator :<\/strong><br \/>David WENDEHENNE<br \/>uB \/ Agro\u00e9cologie<br \/><a href=\"mailto:wendehen@inra.fr\">wendehen@inra.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>uB<\/li><li>AgroSup<\/li><li>INRA<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1807\" class=\"elementor-tab-title\" data-tab=\"7\" role=\"button\" aria-controls=\"elementor-tab-content-1807\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">SCUVIRA - Supercontinuum fibres lasers covering UV to mid-IR applications<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1807\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"7\" role=\"region\" aria-labelledby=\"elementor-tab-title-1807\"><p>The key goal of SCUVIRA project is to build, on the current state-of-the-art, the next generation of Supercontinuum fibre-based sources in the mid-IR (1-15 ) and UV (200-400nm) ranges with characteristics tailored to end-user driven applications such as optical detection, spectroscopy, gas and chemical sensing, fluorescence imaging.<\/p><p><strong>Coordinator :<\/strong><br \/>Fr\u00e9d\u00e9ric SMEKTALA<br \/>uB \/ ICB<br \/><a href=\"mailto:frederic.smektala@u-bourgogne.fr\">frederic.smektala@u-bourgogne.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>FEMTO-ST<\/li><li>uB<\/li><li>UFC<\/li><li>CNRS<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1808\" class=\"elementor-tab-title\" data-tab=\"8\" role=\"button\" aria-controls=\"elementor-tab-content-1808\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">CoILS - Nano-platelets based colloidal integrated light sources for low cost opto-chips<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1808\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"8\" role=\"region\" aria-labelledby=\"elementor-tab-title-1808\"><p>The CoILS project intends to use colloidal emitters for the demonstration of on-chip integrated fluorescent light sources. These colloidal light sources are expected to be a strategic low cost alternative to technologically demanding integrated light emitting diodes (LEDs).<\/p><p><strong>Coordinator :<\/strong><br \/>Jean-Claude WEEBER<br \/>uB \/ ICB<br \/>jean-claude.weeber@u-bourgogne.fr<br \/><br \/><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>uB<\/li><li>CNRS<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1809\" class=\"elementor-tab-title\" data-tab=\"9\" role=\"button\" aria-controls=\"elementor-tab-content-1809\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">Food2C - Providing food to city: conditions to have a sustainable local food model. a frenchvietnamese comparative study<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1809\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"9\" role=\"region\" aria-labelledby=\"elementor-tab-title-1809\"><p>Food2C studies the way that foods are provided to urban consumers today. This multidisciplinary project compares food supply chain organizations in 3 cities in France and Vietnam. Mobilizing the foodshed approach, and considering the use of fermentation as a low-technology method of conservation, Food2C is looking to produce a proof of concept of a low energy local food system, which could be developed in France.<\/p><p><strong>Coordinator :<\/strong><br \/>Hai Vu PHAM<br \/>AgroSup Dijon \/ CESAER<br \/><a href=\"mailto:hai-vu.pham@inra.fr\">hai-vu.pham@inra.fr<\/a><\/p><ul><li><strong>Collaborators :<\/strong><\/li><li>AgroSup<\/li><li>PAM<\/li><li>CSGA<\/li><li>CIRAD<\/li><li>IPSARD<\/li><li>FAVRI<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-18010\" class=\"elementor-tab-title\" data-tab=\"10\" role=\"button\" aria-controls=\"elementor-tab-content-18010\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">TOM - Taste and oral microbiota<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-18010\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"10\" role=\"region\" aria-labelledby=\"elementor-tab-title-18010\"><p>Eating behaviour is a key determinant of human health and inappropriate behaviours can be at the origin of some of the major pathologies affecting the modern societies (obesity, cardiovascular diseases, diabetes). Among the biological factors known to influence eating behaviour, sensory perception (including the sense of taste) plays an important role. Taste perception varies strongly between individuals but the factors at the origin of this variability are not fully understood. For example, different events occurring at the vicinity of the taste receptors on the tongue could modulate taste perception.<br \/>The team has recently suggested that the microbiota at the surface of the tongue could be involved by controlling the taste compounds concentration in the lingual film (the biological material covering the tongue). The aim of this project is to evaluate the contribution of the oral (lingual) microbiota in taste.<\/p><p><strong>Coordinator :<\/strong><br \/>Eric NEYRAUD<br \/>INRA \/ CSGA<br \/><a href=\"mailto:eric.neyraud@dijon.inra.fr\">eric.neyraud@dijon.inra.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>INRA<\/li><li>AgroSup<\/li><li>CGFL<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-18011\" class=\"elementor-tab-title\" data-tab=\"11\" role=\"button\" aria-controls=\"elementor-tab-content-18011\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">GNET WORKS - Google matrix analysis of real complex networks<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-18011\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"11\" role=\"region\" aria-labelledby=\"elementor-tab-title-18011\"><p>GNETWORKS is an interdisciplinary project which will participate to the valorization of the huge amount of data that our society produces into an economic manna. The team will try to make it possible by ranking and organizing these data in order to extract relevant information which could be used by academic research, public institutions, or private companies in various domain such as human and social sciences (digging Wikipedia data), economy (digging world trade data from UN, OECD, WTO), and even health domain (digging omic data).<\/p><p><strong>Coordinator :<\/strong><br \/>Jos\u00e9 LAGES<br \/>CNRS \/ UTINAM<br \/><a href=\"mailto:jose.lages@utinam.cnrs.fr\">jose.lages@utinam.cnrs.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>UTINAM<\/li><li>University of Franche-Comt\u00e9<\/li><li>CNRS<\/li><\/ul><p>\u00a0<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-18012\" class=\"elementor-tab-title\" data-tab=\"12\" role=\"button\" aria-controls=\"elementor-tab-content-18012\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">PlastEAT - Neuro-glial plasticity at meal scale, and eating behavior<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-18012\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"12\" role=\"region\" aria-labelledby=\"elementor-tab-title-18012\"><p>Recent genetic studies formally implicate the brain in obesity pathology and pinpoint genes regulating synaptic plasticity. Rodent data consistently evidence synaptic plasticity in brain circuits controlling appetite. The team, having strong expertise in neuroscience and physiology, aims at identifying the value of this state-dependent plasticity within brain feeding circuits. Highresolution imaging and modern neuroscience research tools will be leveraged to elucidate how food is integrated in discrete \u2018soft\u2019 circuits at the meal scale. Behavioral effects of mealrelated changes in synaptic connection and neuroglial interaction will be fully examined.<br \/>Such new knowledge about intimate mechanisms of satiety might provide new ways to manage obesity and maladaptive eating behaviors.<\/p><p><strong>Coordinator :<\/strong><br \/>Alexandre BENANI<br \/>CNRS \/ CSGA<br \/><a href=\"mailto:alexandre.benani@u-bourgogne.fr\">alexandre.benani@u-bourgogne.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>CSGA<\/li><li>INRA<\/li><li>uB<\/li><li>CNRS<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-18013\" class=\"elementor-tab-title\" data-tab=\"13\" role=\"button\" aria-controls=\"elementor-tab-content-18013\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">INGUSP - Identification of New Genes in Unresolved Syndromic Phenotypes with developmental anomalies combining whole genome sequencing and rna sequencing<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-18013\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"13\" role=\"region\" aria-labelledby=\"elementor-tab-title-18013\"><p>Identifying the genetic cause of developmental anomalies of previously unknown etiology is the first step towards implementing diagnostic tests, understanding disease biological processes, and guiding tailored patient management.<br \/>The main challenges for clinical and molecular delineation of such disorders include access to and careful phenotyping of patients with similar extremely rare disorders, and the mastery of cutting-edge sequencing technologies for data production and interpretation.<br \/>This project will play a major role in the Medical Institute of Genomic Medicine and Immunotherapy, GIMI of Bourgogne Franche-Comt\u00e9, and will contribute to the translational research in the context of the new French \u201cFrance Genomics Medicine 2025\u201d.<\/p><p><strong>Coordinator :<\/strong><br \/>Christel THAUVIN <br \/>uB \/ CHU Dijon \/ UMR 1231 LNC<br \/><a href=\"mailto:christel.thauvin@chu-dijon.fr\">christel.thauvin@chu-dijon.fr<\/a><\/p><p><strong>Collaborators :<\/strong><\/p><ul><li>CHU Dijon<\/li><li>uB<\/li><li>UMR 1231 LNC<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>HERMES &#8211; Spatiotemporal semantics and logical knowledge description of mecHanical objEcts in the era of 4D pRinting and programmable Matter for nExt-generation of CAD systemS An innovative trend promoted by the unique capabilities of additive manufacturing techniques is about the \u201c4D Printing\u201d concept. It is actually the process by which assemblies and parts embodying smart &hellip; <a href=\"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/open-resarch-projects\/\">Continued<\/a><\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":300,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-33931","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages\/33931","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/comments?post=33931"}],"version-history":[{"count":30,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages\/33931\/revisions"}],"predecessor-version":[{"id":45096,"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/pages\/33931\/revisions\/45096"}],"wp:attachment":[{"href":"https:\/\/ubfc-preprod.u-bourgogne.fr\/en\/wp-json\/wp\/v2\/media?parent=33931"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}